Below is a response received about this article from one reader who was allergic. It is possible that you can be allergic to the immune-globulin shot and you should ask your doctor about this possibility and what this may mean for you. A Controversy Pregnancy TreatmentĪny women can be allergic to any medication, vaccine, or treatment given. We also give this shot to Rh Negative mothers who have undiagnosed bleeding during their pregnancy, car accidents, and version (converting a breech to a head-first baby). Of course, it doesn't hurt to ask your doctor, just in case your blood tubes got mixed up with someone else's!Īlthough you didn't ask, I'll also tell you that if you were truly Rh Negative, you need the Rh immune-globulin even after a miscarriage or an ectopic pregnancy, since there can be mixing of maternal and fetal blood there too. So it may be that your new doctor has it right and that your previous doctors didn't have the technology back then to check for the Du variant. But before you go clobbering anyone on the head, do know that this is a recent test. Fear not, getting Rh immune-globulin when you're Rh Positive does no harm, except for your pocketbook.
If this is the case for you, then you received these shots for nothing with your previous pregnancies. If it's positive, then the blood type is corrected to Rh Positive, and no Rh Immune-globulin need be given. Today, any Rh Negative woman should be tested further for the Du variant. It is actually an Rh Positive antigen, which would make a woman "Rh Positive," but since it is very weakly expressed in tests, it's possible to be mistakenly read as Rh Negative. There is a very weak variant called the "Du" variant. But Rh Positive women are identified by their Rh Positive red blood cells. No, it isn't possible to change blood types. Now that we have that out of the way, I can address your question. These "blocking" antibodies therefore protect the fetus.
And since these are bulky molecules, they won't pass on to the fetus. Therefore, no antibodies are made by the mother. Up to 15% of women have Rh Negative blood, but now we can give Rh Immune-globulin, big bulky anti-Rh Positive antibodies which fool the body into thinking the defense has already been launched. If the next baby she's carrying is once again Rh Positive, then her old anti-Rh Positive antibodies, small enough to pass from her circulation through the filtering of the placenta into the baby's bloodstream, will attack the new baby's red blood cells.
But since the mother is RH Negative, it's no big deal, because these antibodies will only attack Rh Positive blood, of which the mother has none. The mother would then make antibodies to this Rh Positive blood. Some blood does get into the maternal bloodstream, and this is just like receiving a blood transfusion from a Rh Positive donor. At the time of delivery when the placenta separates, there is some mixing of maternal and fetal blood. The same thing happens if she has a baby which, through inheritance from the father, would have Rh Positive blood, like the father. If a patient with Rh Negative blood were to receive blood from a Rh Positive donor, she would make antibodies to the Rh Positive blood given to her. Is it possible for an Rh- blood type to switch by itself to Rh+?Ī"Rh" another marker for types of blood, can be either Rh Negative or Rh Positive. What dangers are involved if I receive the antibody while pregnant if I am not Rh-? (I was already given an injection in the first trimester because of bleeding.) I am going to a different doctor for this baby, but the blood test came back stating that I am 0+ and that I am not Rh.
Q In my last two pregnancies my blood test results were that I have Rh- (Rh NEG) blood and received the antibody injections during pregnancy and after delivery.
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